PREN ISO 10801 : DRAFT 2009

1 Scope
2 Normative references
3 Terms and definitions
  3.1 Differential mobility analyzing system (DMAS)
      3.1.1 Differential electrical mobility classifier
            (DEMC)
      3.1.2 Condensation particle counter (CPC)
  3.2 Inhalation chamber system (chamber, head
      only, nose only)
  3.3 Evaporation/condensation nanoparticle
      generator system
4 Principle
  4.1 Generation
  4.2 Preparation of system
5 Requirements
  5.1 Capacity and control
  5.2 Nanoparticle properties
  5.3 Chamber atmosphere
  5.4 System operational safety
6 Characterization of generator performance
7 Nanoparticle generation specifications
  7.1 Chemical purity
  7.2 Size range
  7.3 Number concentration
  7.4 Nanoparticle shape
  7.5 Stability
  7.6 Animal exposure
8 Assessment of results
9 Test report
Annex A (Informative) - Example method for
        evaporation/condensation generation of
        silver nanoparticles
  A.8 Stability of silver nanoparticle generation
      and maintenance of concentrations during
      day inhalation toxicity study
  A.9 Generation of other metal nanoparticles
      (e.g. Gold)

Specifies the metals such, as gold and silver, which have been proven to generate nanoparticles suitable for inhalation toxicity testing using the evaporation/condensation method described in this standard.