PD ISO/TR 22305:2008

Foreword
Introduction
1 Scope
2 Statistical functions for repeatability (r),
  reproducibility (R) of yield measurements and
  compliance tolerances for declared smoke constituent
  yields
  2.1 Statistical functions for repeatability (r) and
      reproducibility (R)
  2.2 A statistical model for compliance tolerances
3 Sources of data
  3.1 International collaborative studies
  3.2 UK Department of Health Cigarette Survey data
4 Comparison of 2003 CORESTA Collaborative Study data with
  those previously reported
  4.1 General
  4.2 Comparison of repeatability r[20] values from CCS-03
      with other collaborative studies
  4.3 Comparison of reproducibility R[20] values from CCS-03
      with other collaborative studies
      4.3.1 General
      4.3.2 Relationship between reproducibility R[20] and
            smoke constituent yield
  4.4 Comparison of R[100] reproducibility values from
      collaborative studies with measurement tolerances
      estimated from the UK Department of Health Cigarette
      Survey data
5 Review of information relevant to setting a compliance
  tolerance for carbon monoxide
  5.1 General
  5.2 Compliance data for current tolerances
  5.3 Confidence intervals associated with yield measurements
  5.4 Statistical models
  5.5 Prediction of a tolerance for CO from the relative
      variability in their reproducibility values
6 Conclusions
7 Recommendations
Annex A (informative) - Background considerations on the choice
                        of sampling procedures
Annex B (informative) - The determination of carbon monoxide in
                        cigarette smoke - Problems in the
                        evaluation of results
Annex C (informative) - Proposals from the UK Tobacco
                        Manufacturers Association for a
                        practicable tolerance for verifying
                        cigarette packet declarations of carbon
                        monoxide (March, 2002)
Annex D (informative) - Analysis of bias measurements from the
                        UK Department of Health Cigarette Survey
Annex E (informative) - ASIA COLLABORATIVE STUDY #11 2002/2003
Annex F (informative) - 2003 CORESTA Collaborative Study Report
                        CORESTA study for the estimation of the
                        repeatability and reproducibility of the
                        measurement of nicotine-free particulate
                        matter, nicotine and CO in smoke using
                        the ISO smoking methods, September 2003
Bibliography

Presents the data and conclusions from a review of international collaborative studies to establish the tolerance for checks of the carbon monoxide yields declared by cigarette manufacturers for their products, as specified in ISO 8243.