ISO 21427-2:2006
Current
The latest, up-to-date edition.
Water quality Evaluation of genotoxicity by measurement of the induction of micronuclei Part 2: Mixed population method using the cell line V79
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08-11-2006
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ISO 21427-2:2006 specifies a method for the determination of genotoxicity of water and waste water using a mammalian in vitro test which detects damage, induced by water-soluble substances, to the chromosomes or the mitotic apparatus of V79 cells from the Chinese hamster.
The micronucleus test allows the identification of substances that cause cytogenetic damage which results in the formation of micronuclei containing lagging chromosome fragments and/or whole chromosomes.
The assay is based on the increase in the frequency of micronucleated cells after incubation with and without metabolic activation.
| DevelopmentNote |
Supersedes ISO/DIS 21427-2. (11/2006)
|
| DocumentType |
Standard
|
| Pages |
22
|
| PublisherName |
International Organization for Standardization
|
| Status |
Current
|
| Standards | Relationship |
| I.S. EN ISO 21427-2:2009&AC:2009 | Identical |
| NBN EN ISO 21427-2 : 2009 COR 2009 | Identical |
| NF EN ISO 21427-2 : 2009 | Identical |
| NEN ISO 21427-2 : 2006 | Identical |
| NEN EN ISO 21427-2 : 2009 C1 2009 | Identical |
| NS EN ISO 21427-2 : 2009 AC 2009 | Identical |
| I.S. EN ISO 21427-2:2009 | Identical |
| PN EN ISO 21427-2 : 2009 | Identical |
| SN EN ISO 21427-2 : 2009 CORR 2009 | Identical |
| UNI EN ISO 21427-2 : 2009 | Identical |
| BS EN ISO 21427-2:2009 | Identical |
| BS 6068-5.45(2006) : 2006 | Identical |
| UNE-EN ISO 21427-2:2009 | Identical |
| DIN EN ISO 21427-2:2009-08 | Identical |
| EN ISO 21427-2:2009 | Identical |
| SN EN ISO 21427-2:2009 | Identical |
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| ISO 16240:2005 | Water quality — Determination of the genotoxicity of water and waste water — Salmonella/microsome test (Ames test) |
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