BS EN ISO 14730:2014

Foreword
Introduction
1 Scope
2 Normative references
3 Terms and definitions
4 Principle
5 Test methods
Annex A (informative) - Example of a membrane
        filtration procedure II
Annex B (informative) - Discard date procedure I
Annex C (informative) - Discard date procedure
Annex D (informative) - Discard date procedure III
Annex E (informative) - Discard date procedure IV
Annex F (informative) - Test organisms from other
        culture collections
Bibliography

Gives a procedure to be used in evaluating the antimicrobial preservative activity of all preserved multidose contact lens care products, and provides guidance on methods for determination of discard date as informative annexes.

This International Standard specifies a procedure to be used in evaluating the antimicrobial preservative activity of all preserved multidose contact lens care products, and provides guidance on methods for determination of discard date as informative annexes.

This test is applicable to products for up to a 28-day discard date.

The test is not applicable to sterile products packaged in unit doses for single use or multidose containers designed with physical barriers to microbial contamination (e.g. aerosol containers).

NOTE1 Principles of the test can be used to extend discard dating beyond 28d. See AnnexesB, C, D and E.

NOTE2 Use of multiple or mixed microbial challenges and/or inclusion of contact lenses or other organic load can influence the apparent antimicrobial activity of a particular product. The evaluation of these variables together with testing against a larger panel of microorganisms and testing of samples from partially used containers can be of value in developing a contact lens care product, but are excluded from the scope of this International Standard.